342. Water Soluble and Bio-Friendly Nanoceria Reduces Laser-Induced CNV Mouse Model of Wet AMD
نویسندگان
چکیده
منابع مشابه
Optical Coherence Tomography versus Fundus Fluorescein Angiography in Diagnosis of Type 2 CNV in Wet AMD
The most common cause of visual impairment in developed countries, particularly over the ages of 55 is Age related macular degeneration (AMD) [1]. Currently, the WHO has estimated that there will be approximately 8 million people affected by AMD by the year 2020 [2]. Whilst AMD was previously an untreatable disease, the wet form is currently treatable with the advent of anti-vascular endothelia...
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آب حاصل از بارش منبع تأمین نیازهای بی شمار جانداران به ویژه انسان است و هرگونه کاهش در کم و کیف آن مستقیماً حیات موجودات زنده را تحت تأثیر منفی قرار می دهد. نوسان سال به سال بارش از ویژگی های اساسی و بسیار مهم بارش های سالانه ایران محسوب می شود که آثار زیان بار آن در تمام عرصه های اقتصادی، اجتماعی و حتی سیاسی- امنیتی به نحوی منعکس می شود. چون میزان آب ناشی از بارش یکی از مولفه های اصلی برنامه ...
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Wet scrubbers are one of the most important air-pollution control devices (APCDs) for the simultaneous removal of various acidic gases and particulates. This study was conducted on a lab-scale self-designed wet scrubber (WSB) system for the treatment of particle-bound water-soluble ions emitted from cooking fumes with/without adding bio-solution (namely, NOE-7F). The concentration and compositi...
متن کاملImmunotherapy for choroidal neovascularization in a laser-induced mouse model simulating exudative (wet) macular degeneration.
Age-related macular degeneration (AMD) is the leading cause of blindness after age 55 in the industrialized world. Severe loss of central vision frequently occurs with the exudative (wet) form of AMD, as a result of the formation of a pathological choroidal neovasculature (CNV) that damages the macular region of the retina. We tested the effect of an immunotherapy procedure, which had been show...
متن کاملVEGF Receptor Blockade Markedly Reduces Retinal Microglia/Macrophage Infiltration into Laser-Induced CNV
Although blocking VEGF has a positive effect in wet age-related macular degeneration (AMD), the effect of blocking its receptors remains unclear. This was an investigation of the effect of VEGF receptor (VEGFR) 1 and/or 2 blockade on retinal microglia/macrophage infiltration in laser-induced choroidal neovascularization (CNV), a model of wet AMD. CNV lesions were isolated by laser capture micro...
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ژورنال
عنوان ژورنال: Molecular Therapy
سال: 2016
ISSN: 1525-0016
DOI: 10.1016/s1525-0016(16)33151-3